Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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1,036 – 1,050 of 5,526 results

1,036

Medchemexpress LLC Z-LYS-SBZL monohydrochloride | 69861-89-8 | 99.7% | C21H27ClN2O3S | 50 MG

Z-LYS-SBZL monohydrochloride is a lysine derivative primarily used for research applications. Amino acid and amino acid derivatives, such as this product, are recognized as beneficial ergogenic dietary substances.

Can influence anabolic hormone secretion
Provide fuel during exercise
Improve mental performance during stress-related tasks
Help prevent exercise-induced muscle damage

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1,037

Medchemexpress LLC Sulfo-ara-F-NMN | 1374663-29-2 | 99.36% | 352.28 | 10 MG

Sulfo-ara-F-NMN (CZ-48) is a mimetic of nicotinamide mononucleotide (NMN). It acts selectively by activating SARM1 and inhibiting CD38 (IC50 around 10 μM), leading to the induction of intracellular cyclic ADP-ribose (cADPR) production.

Mimics nicotinamide mononucleotide
Selectively activates SARM1
Inhibits CD38 (IC50 around 10 μM)
Induces intracellular cyclic ADP-ribose production
For research use only
Store at -20°C under nitrogen
Unstable in solutions; use freshly prepared solutions

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1,038

Medchemexpress LLC Paliperidone (9-Hydroxyrisperidone) | 144598-75-4 | 99.4% | C23H27FN4O3 | 200 MG

Paliperidone (9-Hydroxyrisperidone) is the major active metabolite of Risperidone, functioning as a dopamine D2 and 5-HT2A antagonist. It also exhibits antagonist activity at α1 and α2 adrenergic receptors and H1-histaminergic receptors, demonstrating efficacy as an antipsychotic agent against schizophrenia.

Major active metabolite of risperidone
Dopamine D2 antagonist
5-HT2A antagonist
Antagonist at α1 and α2 adrenergic receptors
Antagonist at H1-histaminergic receptors
Effective antipsychotic agent against schizophrenia
For research use only
Increases caspase-3 activity in neuroblastoma cells
May modulate Akt1/GSK3β pathway to protect SK-N-SH cells from glutamate damage
Can protect SK-N-SH cells from apoptosis induced by glutamate

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1,039

Medchemexpress LLC Buparlisib | 944396-07-0 | 99.8% | C18H21F3N6O2 | 200 MG

Buparlisib is a pan-class I PI3K inhibitor that exhibits blood-brain barrier permeability.

Pan-class I PI3K inhibitor
Blood-brain barrier permeable
Induces apoptosis in multiple myeloma cells
Causes dose-dependent growth inhibition in tested multiple myeloma cell lines

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1,040

Medchemexpress LLC Chlormezanone | 80-77-3 | 99.8% | 200 MG

Chlormezanone resembles benzodiazepine, and its action is similar to benzodiazepine-type agents. It is used as an anxiolytic and a muscle relaxant.

Used as an anxiolytic and a muscle relaxant.
Resembles benzodiazepine and acts similarly to benzodiazepine-type agents.
Available in solid form (white to off-white).
For research use only.

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1,041

Medchemexpress LLC Acotiamide monohydrochloride trihydrate | 773092-05-0 | 99.8% | 500 MG

Acotiamide monohydrochloride trihydrate is an orally active, selective, and reversible acetylcholinesterase inhibitor, with an IC50 of 1.79 μM. It can enhance gastric contractility and accelerate delayed gastric emptying. This compound has potential for the research of functional dyspepsia involving gastric motility dysfunction and intestinal inflammatory conditions.

Acts as an orally active, selective, and reversible acetylcholinesterase inhibitor.
Enhances gastric contractility.
Accelerates delayed gastric emptying.
Has potential for research into functional dyspepsia involving gastric motility dysfunction and intestinal inflammation.

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1,042

Medchemexpress LLC Subasumstat | 1858276-04-6 | 578.10 | 200 MG

Subasumstat (TAK-981) is a first-in-class and selective inhibitor of the SUMOylation enzymatic cascade, with potential immune-activating and antineoplastic activities.

Selective inhibitor of SUMOylation enzymatic cascade.
Potential immune-activating and antineoplastic activities.
Increases production of type 1 IFN, activating innate effector cells and enhancing antitumor innate immune responses.
Induces activation of DCs in naive Balb/c mice.

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1,043

Medchemexpress LLC Mono-2-ethyl-5-carboxypentyl terephthalate-d4 | 1684398-42-2 | >85.0% | 312.35 g·mol⁻¹ | C16H16D4O6 | 1 MG

Mono-2-ethyl-5-carboxypentyl terephthalate-d4 is a deuterium-labeled analogue of mono-2-ethyl-5-carboxypentyl terephthalate supplied for use as an analytical tracer and internal standard. It enables accurate quantitation in trace analysis workflows and is intended for use in NMR, GC-MS, and LC-MS methods.

Isotope-labeled internal standard for quantitative analysis.
Compatible with NMR, GC-MS, and LC-MS workflows.
Deuterium labels provide clear mass shift for accurate detection.
Supplied as a small-quantity vial suitable for calibration and method development.
Certificate of Analysis and handling documentation available on request.

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1,044

Medchemexpress LLC Ralinepag | 1187856-49-0 | 99.3% | 431.91 | 200 MG

Ralinepag is a potent, orally bioavailable, and non-prostanoid prostacyclin (IP) receptor agonist. It is suitable for research applications.

Potent IP receptor agonist
Orally bioavailable
Non-prostanoid
EC50s of 8.5 nM for human IP receptor
EC50s of 530 nM for rat IP receptor
EC50s of 850 nM for human DP1 receptor
Inhibits ADP-induced human platelet aggregation with an IC50 of 38 nM
No significant effect on cytochrome P450 enzymes
No effect on hERG channel functional activity

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1,045

Medchemexpress LLC AM095 | 1345614-59-6 | 99.7% | 478.47 | 200 MG

AM095 is a selective LPA1 receptor antagonist known for its potent inhibition of LPA-induced calcium flux in human and mouse LPA1-transfected CHO cells. It demonstrates an exceedingly low IC50 for human (0.025 μM) and mouse (0.023 μM) cells, positioning it as a valuable tool for research involving LPA1 receptor pathways.

Selective LPA1 receptor antagonist.
Potently inhibits LPA-induced calcium flux.
Applicable in studies involving human or mouse LPA1-transfected CHO cells.
Useful for researching LPA1 receptor pathways.

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1,046

Medchemexpress LLC Sulfo-SMCC sodium | 92921-24-9 | 99.9% | 200 MG

Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker. It contains N-hydroxysuccinimide (NHS) ester and maleimide groups, which allow it to react with primary amines and sulfhydryl groups, respectively. This product is intended for research use only.

Reacts with primary amines and sulfhydryl groups
Suitable for ADC conjugation
Noncleavable linker
Used in various biological research applications

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1,047

Medchemexpress LLC O-tert-Butyl-N-carbobenzoxy-L-serine methyl ester | 1872-59-9 | MFCD00037803 | 309.36 | 5 G

O-tert-Butyl-N-carbobenzoxy-L-serine methyl ester is a serine derivative. Amino acids and amino acid derivatives have been commercially used as ergogenic supplements, influencing the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress-related tasks, and preventing exercise-induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances.

Serine derivative.
Beneficial as ergogenic dietary substances.
Influences secretion of anabolic hormones.
Supplies fuel during exercise.
Improves mental performance during stress-related tasks.
Prevents exercise-induced muscle damage.

Pricing & Availability

1,048

TARGETMOL CHEMICALS INC FENGABINE 5MG

Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Fengabine (SL-79229) is a GABA receptor agonist with antidepressant activity and is used to treat depression. purity: 98%

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1,049

Apexbio Technology LLC Pimobendan 74150-27-9 200mg

Pimobendan (CAS 74150-27-9) is a small molecule that acts as a selective phosphodiesterase 3 (PDE3) inhibitor exhibiting an IC50 of 0 32 M By inhibiting PDE3 activity Pimobendan modulates intracellular cyclic nucleotide levels thereby influencing cellular signaling pathways involved in cardiovascular function This compound is utilized in biomedical research to investigate PDE3-mediated mechanisms and their implications in cardiac physiology and related disease models

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1,050

Apexbio Technology LLC Rimantadine 13392-28-4 200mg

Rimantadine (13392-28-4) is a small-molecule inhibitor targeting the M2 ion channel protein of influenza A virus It is designed to specifically block the M2 channel thereby inhibiting the viral uncoating process and preventing subsequent viral entry into host cells Rimantadine exerts its biological activity primarily through inhibition of the M2 ion channel In in vitro studies rimantadine demonstrates antiviral activity with reported IC50 values typically ranging from approximately 0 1 to 1 M depending on virus strain and experimental context Based on these pharmacological properties rimantadine holds research potential in investigating influenza A viral replication resistance mutations infection pathways and in evaluating antiviral activity and establishing infection models in vitro

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Quinolines and derivatives

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Medchemexpress LLC Z-LYS-SBZL monohydrochloride | 69861-89-8 | 99.7% | C21H27ClN2O3S | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Sulfo-ara-F-NMN | 1374663-29-2 | 99.36% | 352.28 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Paliperidone (9-Hydroxyrisperidone) | 144598-75-4 | 99.4% | C23H27FN4O3 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Buparlisib | 944396-07-0 | 99.8% | C18H21F3N6O2 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Chlormezanone | 80-77-3 | 99.8% | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Acotiamide monohydrochloride trihydrate | 773092-05-0 | 99.8% | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Subasumstat | 1858276-04-6 | 578.10 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Mono-2-ethyl-5-carboxypentyl terephthalate-d4 | 1684398-42-2 | >85.0% | 312.35 g·mol⁻¹ | C16H16D4O6 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ralinepag | 1187856-49-0 | 99.3% | 431.91 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AM095 | 1345614-59-6 | 99.7% | 478.47 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Sulfo-SMCC sodium | 92921-24-9 | 99.9% | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC O-tert-Butyl-N-carbobenzoxy-L-serine methyl ester | 1872-59-9 | MFCD00037803 | 309.36 | 5 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More